Apple & Pear Study

Study Type

General Health & Wellbeing

Study Purpose

The purpose of the APPLE & PEAR research study is to determine why women carry weight differently and how it may affect health.

About the Study

Did you know that where you carry your weight may affect your health?

The body shape of women varies between having the majority of fat either above the waist (apple shape) or below the waist (pear shape). Since pear-shaped women tend to have better health, we will study what restricts apple-shaped women from being pear-shaped at the cellular level and thus having the same level of health. The study will look at differences in the formation of new fat cells between the fat tissue from the abdomen and the thigh.

Study Design

Number of visits:

  • 1 Screening visit
  • 13 Clinic visits

Study procedures:

  • Height, weight, vitals
  • Urine collection and blood draws
  • Oral Glucose Tolerance Test (OGTT)
  • Fat biopsy
  • DXA scan
  • MRI
  • MRS
Eligible participants may take study medication for up to 16 weeks. All study procedures and medications will be provided at no cost to participants.

Study Qualifications

  • Female
  • Age:18-40 years old
  • Weight: BMI (27-38) calculate your BMI
  • No smoking within the past 6 months

Study Duration

6 months


Earn up to $1400 for participation.

Study Contact

If you are interested in volunteering for the Apple & Pear Study, click here to screen online, call 225-763-3000 or email

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


English Calculation
Enter Your Weight: 
Enter Your Height: 
 ft.  in.
Your BMI: