D2d Study

Study Type


Study Purpose

Are you at risk for type 2 diabetes? Risk factors include: family history of diabetes, overweight, sedentary lifestyle and diabetes during pregnancy.

The U.S. Centers for Disease Control and Prevention estimated in 2012 that 12.3% of adults in Louisiana had been told by their doctor that they have diabetes. This national research study will investigate whether taking vitamin D can prevent diabetes in people who are at high-risk for the disease. As a food ingredient or dietary supplement, vitamin D is generally recognized as safe. However, we do not know if vitamin D is effective in preventing diabetes.

About the Study

The national D2d study is a clinical research trial for people at high risk for developing diabetes. Study participants will be seen at Pennington Biomedical Research Center and followed for four years. During the study, participants will have testing for diabetes at no cost. D2d is sponsored by the National Institutes for Health, National Institute of Diabetes and Digestive and Kidney Diseases, NIH Office of Dietary Supplements, the American Diabetes Association and the National Diabetes Education Program.

Study Design

Number of visits:

  • 1 screening visit
  • 3 clinic visits at the beginning of the study
  • Annual and semi-annual outpatient visits until end of study

Study procedures:

  • Height, weight, vitals, physical exam
  • Waist measurement
  • Oral Glucose Tolerance Test (OGTT)
  • Pregnancy test
  • Blood draws and urine samples
  • Questionnaires

All study procedures will be provided at no cost to participants.

Study Qualifications

  • Age:≥ 30 years old (≥ 25 for American-Indians, Alaska Natives, Native Hawaiians, or Other Pacific Islanders)
  • Weight: BMI (≥ 24 [>22.5 for Asians] and ≤ 42) calculate your BMI
  • Pre-diabetic

Study Duration

Up to 4 years


Earn up to $150/year 1 and up to $75/year for years 2-4 for participation.

Study Contact

If you are interested in volunteering for the D2d study, click here to screen online, call 225-763-3000 or email clinicaltrials@pbrc.edu.

If you think you may be eligible, please click the button below to screen online.


Please do not fill out this questionnaire for anyone other than yourself unless you are their legal guardian.
If you know someone who may be interested please direct them to the site or have them call us directly at 225-763-3000.


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